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Ubudlelwano phakathi kwe-resveratrol nempilo yabantu
2024-07-24 11:56:08
I-Resveratrol, inhlanganisela ye-polyphenol engeyona i-flavonoid ye-organic, iyi-antitoxin ekhiqizwa izitshalo eziningi lapho ivuselelwa, ne-chemical formula C14H12O3. Ingahlanganiswa emaqabunga amagilebhisi nezikhumba zamagilebhisi futhi iyisithako se-bioactive ewayinini kanye nejusi yamagilebhisi.I-Resveratrolkanye nokuphuma kwawo kutholakala ikakhulukazi ezinhlotsheni zezitshalo ezingama-72 ezizukulwaneni ezingama-31 kanye nemindeni engama-21 njengeVitis, iPolygonum, amantongomane kanye ne-veratrol, okuhlanganisa nezitshalo ezivamile zokwelapha ezifana nefindo, i-cassia kanye ne-mulberry, kanye nezitshalo ezifana namagilebhisi namakinati. . Imithombo yemvelo eyinhloko yei-resveratrolkukhona amafindo namagilebhisi.I-Resveratrolimuncwa kalula ngomlomo futhi ikhishelwe emchamweni nasezindleleni ngemva kokugayeka kokudla. Ukuhlolwa kwe-in vitro nezilwane kuye kwabonisa lokhoi-resveratroline-antioxidant, anti-inflammatory, anticancer kanye nemiphumela yokuvikela inhliziyo. Ihlola ubudlelwano phakathii-resveratrolkanye nempilo yabantu ihambisana nokugqugquzela ukucutshungulwa okujulile nokusetshenziswai-resveratrolkanye nokwenza ngcono impilo yabantu.
ISIPHETHO
Ukuhlola kubonise ukuthi ukungenelela kwangaphambili ngei-resveratrolingavimbela ukulimala kwesibindi kwe-iris. Ngesikhathi esifanayo,i-resveratrolkwatholakala ukuthi kuvimbela ukuvuvukala kwesibindi ngesikhathi se-HIRI ngokuthinta ama-neutrophils. Indlela yokwenza ngayoi-resveratrolelawula ama-neutrophils iwukuvimbela ukusinda kwama-neutrophils, umjikelezo weseli, ukufuduka kwe-chemotaxis, ukucindezeleka kwe-oxidative, ukukhishwa kwe-cytokine kanye ne-endothelin-1 autocrine ngokuvimbela indlela yokusayina ye-ERK. Le datha inikeza ubufakazi obengeziwe bemiphumela ye-immunomodulatoryi-resveratrolfuthi sithuthukise ukuqonda kwethu amasu omzimba wokuthuthukisa i-HIRI.
Ireferensi:
U-WANG YN, SUN XJ, HAN XT, et al.I-Resveratrolithuthukisa ukulimala kwe-ischemia-reperfusion yesibindi ngokuvimbela ama-neutrophils ngendlela ye-ERK yokusayina[J]. I-Biomedicine & Pharmacotherapy, 2023, 160: 114358. DOI:10.1016/j.biopha.2023.114358.
Ngokusekelwe ezifundweni eziphelele ze-preclinical,i-resveratrolinemiphumela ye-chemoprotective ne-chemosensitizing ngokusebenzisa izindlela zokulwa ne-plasticity, i-antioxidant, anti-inflammatory, kanye ne-pro-apoptotic. Ngaphezu kwemiphumela yayo ye-anticancer,i-resveratrolfuthi isebenza njengomengameli wobuthi obubangelwa ngamakhemikhali kumaseli/izicubu ezivamile. Njengesidakamizwa esilwa nesimila (esiqondise izindlela eziningi), inhlanganisela yezidakamizwa ithuthukisa umphumela wayo wokwelapha ngokusebenzisa i-superposition kanye ne-synergy, futhi inciphisa imiphumela yokumelana nokwelashwa ngamakhemikhali.
XHUMANA NATHI
Umakhalekhukhwini: 86 18691558819
Irene@xahealthway.com
www.xahealthway.com
Wechat: 18691558819
WhatsApp: 86 18691558819
Irene@xahealthway.com
www.xahealthway.com
Wechat: 18691558819
WhatsApp: 86 18691558819
Kafushane, lesi sihloko sibuyekeza umphumela wokuzwela kwamakhemikhali wei-resveratrolkumaseli wesimila kuya emithini ye-chemotherapy ngokombono we-cell plasticity, ebaluleke kakhulu ekuguquguqukeni kwamaseli ku-TME ngesikhathi sokuguqulwa kweseli yesimila kanye ne-metastasis. Lokhu futhi kunikeza umfutho omusha wocwaningo olwengeziwe mayelana ne-epigenetics yomdlavuza kanye ne-resveratrol-mediated plasticity inhibition, okuphakamisa ngokuqinile ukuthii-resveratrol, njenge-phytochemical esebenzayo, izobamba iqhaza ekuvimbeleni nasekwelapheni kwe-CRC esikhathini esizayo. indima ebalulekile.
Ukuze uthole okwengeziweulwazimayelana nemikhiqizo namasevisi ethu sicela usithinte.
Ulwazi:https://www.xahealthway.com/
I-Resveratrol:
https://www.xahealthway.com/polygonum-cuspidatum-extract-trans-resveratrol-98-hplc-product/
https://www.xahealthway.com/polygonum-cuspidatum-extract-trans-resveratrol-98-hplc-product/