Ngaphezu kwezinguquko zendlela yokuphila kanye nokubambelela emikhubeni emihle, ukwengezwa kwangaphandle kwezinto zemvelo ezilwa nokuguga nakho kuyindlela elula futhi elula yokulwa nokuguga. Ngokusho kwesiqondiso socwaningo (i-NAD + metabolic regulation) kanye nemiphumela yocwaningo lwamanje lokulwa nokuguga kanye nezicelo ezithinteka kakhulu.futhi"inkungu yobuchopho"ngemuva kwe-COVID-19,thina'ngingathanda ukwethula okuhle okuninganaizithako zokulwa nokugugakusuka ezithasiselweni zokuthengisa ezishisayo ku-Amazon.
1. Izithasiselo ze-NAD+ (NMN, NR, NADH)
Amazinga e-NAD+ ehla ngokuya ngeminyaka, okuholela ekuwohlokeni okuzwela kumazinga e-NAD+. Umndeni we-acetylase (ama-sirtuins, avame ukukhangiswa njengamaprotheni okuphila isikhathi eside) awukwazi ukugcina umsebenzi ojwayelekile, ukuze imisebenzi eminingi enenzuzo empilweni exhunywe ama-sirtuin ayikwazi ukwenziwa, okungenye yezizathu ezibalulekile zokuguga.Iukuthathwa kwe-NMN (i-nicotinamide mononucleotide), i-NR (i-nicotinamide riboside) noma i-NADH (i-nicotinamide adenine dinucleotide) ingasiza amangqamuzana enyuse amazinga e-NAD+, futhi lawa akhona ngokwemvelo kumaseli nokudla kwemvelo..Njengamanje, kunamakhulu ezifundo zomtholampilo ku-NMN, NR, kanye ne-NADH, ezigxile ezicini ezihlukahlukene ezifana nokulwa nokuguga, isifo sikashukela, i-metabolism, kanye nokuqonda.
2. I-Pyrroloquinoline quinone (PQQ)
I-PQQ iyi-coenzyme ye-redox kanye ne-antioxidant eqinile. Ikhona nasekudleni okuhlukahlukene. Okuqukethwe kwe-PQQ emzimbeni womuntu kuphansi kakhulu. I-PQQ emangqamuzaneni omuntu ingase ivele ekudleni noma kuma-microorganisms. Ukudla okune-PQQ eyengeziwe kufaka phakathi: i-natto, i-parsley, itiye eliluhlaza, isithelo sekiwi, i-papaya, i-tofu, njll. Izinzuzo zezempilo ezingaba khona ze-PQQ zifaka: ukwenza ngcono ukulala, ukulwa nesifo sikashukela, ukulwa nokuqaqamba kwamalunga, ukulwa nokukhumuzeka kwamathambo, ukwehlisa ukulimala kwe-ischemia-reperfusion yenhliziyo, ukuvimbela i-tyrosinase, ukuthuthukisa inzalo.
3. I-Fisetin
I-Fisetin, eyaziwa nangokuthiI-Smoke Tree Extract , i-flavonol etholakala esitshalweni kanye ne-pigment yesitshalo evamile etholakala emifino eminingi evamile nezithelo ezifana nama-strawberries, ama-apula, ama-persimmons, u-anyanisi, namakhukhamba. Yandisa isikhathi sokuphila samagundane amadala ngo-10%, inciphisa izimpawu zokuguga ezicutshini, futhi ibambezele izifo ezihlobene nokuguga. Indlela yokulwa nokuguga ye-fisetin iwukuthi ingasusa amaseli enzwa futhi isebenze njenge-synolytic. Ukuqoqwa kwamangqamuzana ezinzwa nakho kuyimbangela ebalulekile yokuguga kanye nezifo ezihlobene nokuguga. Ucwaningo luye lwathola ukuthi izinzuzo zezempilo ezingase zibe khona ze-fisetin zihlanganisa: i-anti-oxidation, anti-inflammation, ukuvikela inhliziyo, ukuvikelwa kwengqondo, ukuvimbela ukukhuluphala kanye nokuphazamiseka kwe-metabolic.
4. Urolithin A
I-Urolithin A iqukethe izicubu ezihlukahlukene zomzimba womuntu. Kodwa i-urolithin A ayiyona i-molecule yemvelo ekudleni futhi ikhiqizwa amanye amagciwane amathumbu agaya i-ellagic acid nama-ellagitannins. Ama-precursors e-urolithin A - i-ellagic acid ne-ellagitannins - atholakala kakhulu ekudleni okuhlukahlukene, njengamapomegranati, ama-strawberry, ama-raspberries, nama-walnuts. Ukuthi umzimba womuntu ungakwazi yini ukukhiqiza i-urolithin A eyanele ngemva kokungenisa lezi zandulela futhi kunqunyelwe ukuhlukahluka kwamagciwane amathumbu. Ukuguga kuholela ekwehleni kwekhono le-autophagic lamaseli, okuholela ekuqongeleleni kwe-mitochondria eyonakele, kudala ukucindezeleka okwenziwe nge-oxidative, futhi kukhuthaze ukuvuvukala. I-Urolithin A ithuthukisa impilo ye-mitochondrial ngokwandisa i-autophagy.
5. I-Spermidine
I-Spermidine i-polyamine yemvelo okugxilwe kwayo kwe-intracellular kuncipha ngesikhathi sokuguga kubantu, futhi kungase kube khona ukuxhumana phakathi kokunciphisa ukuhlushwa kwe-spermidine kanye nokukhubazeka okuhlobene neminyaka.Imithombo yokudla enkulu ye-spermidine ihlanganisa okusanhlamvu okuphelele, ama-apula, amapheya, amahlumela emifino, amazambane, nabanye. .Imiphumela engaba khona ye-spermidine ihlanganisa: ukwehlisa umfutho wegazi, ukuqinisa ukuzivikela kwe-antioxidant, ukwandisa i-arginine bioavailability, ukunciphisa ukuvuvukala, ukunciphisa ukuqina kwemithambo, ukulawula ukukhula kwamangqamuzana.
Isikhathi sokuthumela: Mar-02-2023
