Umsebenzi obalulekile we-NMN

Umsebenzi obalulekile weNMNakugcini nje ngokuqeda ukuguga. Izinhlangano ezigunyaziwe ezifana neCell neNature zidalule kabanzi imisebenzi ye-NMN. Imisebenzi ye-NMN ingafingqwa kanjena:
umsebenzi obalulekile we-NMN awugcini nje ngokulwa nokuguga. Izinhlangano ezigunyaziwe ezifana neCell neNature zidalule kabanzi imisebenzi ye-NMN. Imisebenzi ye-NMN ingafingqwa kanjena:

Umsebenzi 1: Hlela amandla adingekayo ukukhiqiza ngaphezu kwama-95% emisebenzi yempilo
I-Mitochondria emangqamuzaneni omuntu yizitshalo zamandla zamaseli.I-NAD+ (coenzyme I) iyi-coenzyme ebalulekile ku-mitochondria ye-aerobic oxidation kanye ne-metabolism ye-tricarboxylic acid.umjikelezo wokukhiqiza i-molecule yamandla i-ATP, ukuze izinhlobo ezintathu ezinkulu zemisoco etholwe umzimba womuntu, ushukela, amafutha kanye namaProtein iguqulwe ibe amandla nezinye izinto ezidingekayo emisebenzini ye-metabolic ngomjikelezo we-tricarboxylic acid.

Umsebenzi 2: Ukulungisa izakhi zofuzo (DNA)
I-NAD+ (coenzyme I) isetshenziswa njenge-substrate ukukhiqiza i-enzyme yokulungisa izakhi zofuzo i-PARP1. Ngesikhathi esifanayo, i-PARP1 eyenziwe yangasebenzi iphrotheni i-DBC1 ingahlukaniswa futhi ibuyiselwe emsebenzini. I-PARP1 ingakwazi ukuphinda ibhale kabusha izakhi zofuzo ezilimele ngokuya ngokulandelana okujwayelekile kofuzo ukulungisa ufuzo.

Umsebenzi 3: Anti-ukuguga
I-NAD+ (Coenzyme I) igcina ukuxhumana kwamakhemikhali phakathi kwe-nucleus kanyei-mitochondria. Uma lokhu kuxhumana kuba buthaka, kuzoholela ekwehleni kwe-mitochondrial. Ukwehla kwe-mitochondria kuyimbangela ebalulekile yokuguga kwamangqamuzana. I-NAD+ (Coenzyme I) ingagcina ukubonakaliswa okuvamile kwezakhi zofuzo futhi igcine amaseli. Umsebenzi wayo wesikhathi esigcwele ubambezela inqubo yamangqamuzana aguqukela kumaseli abomvu tebhu.

Umsebenzi 4: Gcina amandla okuvuselela ama-capillary
Amaseli emisipha akhulula izici zokukhula ngesikhathi sokuzivocavoca, futhi amangqamuzana e-capillary epidermal athola izici zokukhula ukuze asheshise ukukhula. Le nqubo incike kuphrotheni yokuphila isikhathi eside i-Sirtuin1 ekhiqizwaNAD+(Coenzyme I). Lapho umuntu emdala, i-NAD+ (Coenzyme I) iyancipha, nokuzivocavoca Umphumela wokukhuthaza ukukhula kwemisipha uzoba mubi kakhulu.

Umsebenzi 5: Imetabolism yotshwala
I-Alcohol metabolism ihlukaniswe ngezinyathelo ezimbili. Okokuqala, iguqulwa ibe i-acetaldehyde enobuthi, bese iqhubeka nokubola ibe i-acetic acid engenangozi. Isinyathelo ngasinye kufanele sincike ku-catalysis ye-coenzyme I.

Ngokusho kwezibalo ezifanele, abasebenzisi abathatha njaloNMNuzothola imiphumela elandelayo: amandla athuthukisiwe, amandla omzimba athuthukisiwe, ukuncipha kwamafutha, ukuzuza kwemisipha, ikhono elithuthukisiwe lokuzivivinya, ukuthuthukiswa kwesikhumba, ukuncishiswa kokulahlekelwa izinwele, ukukhula kwezinwele, ukuthuthukiswa kokulala, ukulawulwa kwewashi lezinto eziphilayo, nokulawulwa kwamasosha omzimba. , ukuncishiswa kokungezwani komzimba, ukuthuthukiswa kokusebenza kocansi, ukukhulisa isifiso sokudla, ukunciphisa ukukhathala okubukwayo, ukuthuthukiswa kwamehlo, ukuthuthuka kwemizwa, ukwehla koshukela osegazini, ukwehlisa umfutho wegazi ophakeme we-systolic blood pressure, hypotension normalization, ukuqunjelwa, njll., okuhlukahluka kumuntu nomuntu.

Amaqembu asebenzayo we-NMN
1. Abantu asebekhulile, ababesiza ekuthuthukiseni izifo ezehlukene zokuguga;
2. Abantu abaneminyaka ephakathi, baqede noma banciphise izinkinga ezihlukahlukene zezempilo, njengokukhathala okungapheli, ukungalali kahle, ukulahlekelwa ukubona, njll.;
3. Labo abangalali ebusuku bayosheshisa ukululama komzimba;
4. Abazohlolwa, bathuthukise ikhono labo lokumelana nokucindezeleka futhi bagcine izingqondo zabo zicacile;
5. Abantu abanemithamo ephezulu yokukhipha imisebe, njengezazi ze-radiologists, abahlengikazi, nabasebenzi basemoyeni, bangathuthukisa ikhono labo lokulungisa izakhi zofuzo ezilinyazwe imisebe;
6. Iziguli ezinomdlavuza, zisiza iziguli ngemva kokwelashwa ngeradiotherapy nokwelashwa ngamakhemikhali ukuze zilungise izakhi zofuzo, zithuthukise amasosha omzimba, futhi zisheshise ukululama ngokomzimba;
7. Kwabakhi bomzimba, sheshisa ukukhula kwemisipha;
8. Abasubathi, thuthukisa amazinga wamandla kanye nesivinini sokusabela;
9. Kubantu abaphuzayo, ingathuthukisa ikhono lokukhulula i-hangover, ivikele isibindi, futhi ilungise izakhi zofuzo ezilinyazwe ubuthi be-acetaldehyde;
10. Kwababhemayo, yehlisa inkanuko;
11. Kubantu abacindezelekile, khulisa amazinga e-dopamine, uthuthukise isimo sengqondo, ukhuphule ukutholakala kwegazi ebuchosheni, futhi unciphise ukuncipha kobuchopho okubangelwa ukucindezeleka;
12. Kwabesifazane abaneminyaka ephakathi kanye nasebekhulile, thuthukisa impilo yesikhumba futhi ubambezele ukuguga kwesikhumba;
13. Abanye okungenzeka bane-NAD+ ephansi (coenzyme I).