Amaphilisi e-l-glutathione enziwe abe mhlophe esikhumba anciphise inqwaba yempushana ethengiswayo

 Isingeniso se-Glutathione

I-Glutathione iyi-tripeptide eyakhiwe i-Glutamic acid, i-Cysteine ​​​​ne-Glycine. Ingenye yezinto ezibaluleke kakhulu zemvelo ze-antioxidant emzimbeni womuntu kanye ne-molecule eyinhloko ekugcineni impilo nokusebenza kwamaseli. I-Glutathione ikhona esimweni sokulingana phakathi kwefomu elincishisiwe (i-GSH) kanye nefomu eline-oxidized (GSSG) ngaphakathi kwamaseli. Inciphisa ukulimala kwama-radical mahhala kumaseli ngokusabela nawo, iwaguqule abe yizinhlanganisela ezingenabungozi. Ngaphezu kwalokho, i-glutathione iphinde ibe namandla okuvuselela uvithamini C no-vitamin E, ithuthukise ukusebenza kwayo kwe-antioxidant. Ngaphandle kokuba i-antioxidant, i-glutathione iphinde ihileleke emisebenzini ehlukahlukene yamaselula, njengokuqeda ubuthi, ukugcina ibhalansi ye-apoptosis, ukulungisa umonakalo we-DNA, njll. Iphinde ihileleke ekuphenduleni okubalulekile kwe-biochemical efana ne-protein synthesis kanye nokusayina kwe-intracellular. Umzimba womuntu ungahlanganisa i-glutathione ngokwayo, kodwa ngokukhula kanye nomthelela wezici zemvelo, izinga le-glutathione emzimbeni lingase lehle. Ngaphezu kwalokho, izifo ezithile nokucindezeleka kwemvelo (njengokucindezeleka kwe-oxidative, ukuchayeka okunobuthi, njll.) kungase futhi kuholele ekwehleni kwamazinga e-glutathione. Ngakho-ke, ukwesekwa kwe-glutathione kunganikeza ukwesekwa kwe-antioxidant, kuthuthukise ukumelana nokuvikelwa kwamaselula. Ngamafuphi, i-glutathione iyinto ebalulekile ye-antioxidant kanye ne-molecule yokulawula ukusebenza kwamaseli, edlala indima ebalulekile ekugcineni impilo nokusebenza kwamangqamuzana nokuvimbela izifo.